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Structural features of coronavirus SARS-CoV-2 spike protein: Targets for vaccination

Various human pathogenic viruses employ envelope glycoproteins for host cell receptor recognition and binding, membrane fusion and viral entry. The spike (S) glycoprotein of betacoronavirus SARS-CoV-2 is a homotrimeric class I fusion protein that exists in a metastable conformation for cleavage by h...

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Detalles Bibliográficos
Autores principales: Sternberg, Ariane, Naujokat, Cord
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336130/
https://www.ncbi.nlm.nih.gov/pubmed/32645344
http://dx.doi.org/10.1016/j.lfs.2020.118056