Reduced Ebola vaccine responses in CMV(+) young adults is associated with expansion of CD57(+)KLRG1(+) T cells

CMV is associated with immunosenescence and reduced vaccine responses in the elderly (>70 yr). However, the impact of CMV in young adults is less clear. In this study, healthy UK and Senegalese adults aged 18–50 yr (average, 29 yr) were vaccinated with the Ebola vaccine candidate chimpanzee adeno...

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Detalles Bibliográficos
Autores principales: Bowyer, Georgina, Sharpe, Hannah, Venkatraman, Navin, Ndiaye, Pierre Birahim, Wade, Djibril, Brenner, Nicole, Mentzer, Alex, Mair, Catherine, Waterboer, Tim, Lambe, Teresa, Dieye, Tandakha, Mboup, Souleymane, Hill, Adrian V.S., Ewer, Katie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336307/
https://www.ncbi.nlm.nih.gov/pubmed/32413101
http://dx.doi.org/10.1084/jem.20200004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336307/
https://www.ncbi.nlm.nih.gov/pubmed/32413101
http://dx.doi.org/10.1084/jem.20200004

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