Impact of checkpoint blockade on cancer vaccine–activated CD8(+) T cell responses

Immune and molecular profiling of CD8 T cells of patients receiving DC vaccines expressing three full-length melanoma antigens (MAs) was performed. Antigen expression levels in DCs had no significant impact on T cell or clinical responses. Patients who received checkpoint blockade before DC vaccinat...

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Detalles Bibliográficos
Autores principales: Santos, Patricia M., Adamik, Juraj, Howes, Timothy R., Du, Samuel, Vujanovic, Lazar, Warren, Sarah, Gambotto, Andrea, Kirkwood, John M., Butterfield, Lisa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336310/
https://www.ncbi.nlm.nih.gov/pubmed/32369107
http://dx.doi.org/10.1084/jem.20191369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336310/
https://www.ncbi.nlm.nih.gov/pubmed/32369107
http://dx.doi.org/10.1084/jem.20191369

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