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Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells

Cytotoxic T cells play a key role in adaptive immunity by killing infected or cancerous cells. While the transcriptional control of CD8 T cell differentiation and effector function following T cell activation has been extensively studied, little is known about epigenetic regulation of these processe...

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Detalles Bibliográficos
Autores principales: Tay, Rong En, Olawoyin, Olamide, Cejas, Paloma, Xie, Yingtian, Meyer, Clifford A., Ito, Yoshinaga, Weng, Qing Yu, Fisher, David E., Long, Henry W., Brown, Myles, Kim, Hye-Jung, Wucherpfennig, Kai W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336313/
https://www.ncbi.nlm.nih.gov/pubmed/32374402
http://dx.doi.org/10.1084/jem.20191453