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Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells
Cytotoxic T cells play a key role in adaptive immunity by killing infected or cancerous cells. While the transcriptional control of CD8 T cell differentiation and effector function following T cell activation has been extensively studied, little is known about epigenetic regulation of these processe...
Autores principales: | Tay, Rong En, Olawoyin, Olamide, Cejas, Paloma, Xie, Yingtian, Meyer, Clifford A., Ito, Yoshinaga, Weng, Qing Yu, Fisher, David E., Long, Henry W., Brown, Myles, Kim, Hye-Jung, Wucherpfennig, Kai W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336313/ https://www.ncbi.nlm.nih.gov/pubmed/32374402 http://dx.doi.org/10.1084/jem.20191453 |
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