Blimp-1 is essential for allergen-induced asthma and Th2 cell development in the lung

A Th2 immune response is central to allergic airway inflammation, which afflicts millions worldwide. However, the mechanisms that augment GATA3 expression in an antigen-primed developing Th2 cell are not well understood. Here, we describe an unexpected role for Blimp-1, a transcriptional repressor t...

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Detalles Bibliográficos
Autores principales: He, Kun, Hettinga, Angela, Kale, Sagar Laxman, Hu, Sanmei, Xie, Markus M., Dent, Alexander L., Ray, Anuradha, Poholek, Amanda C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336314/
https://www.ncbi.nlm.nih.gov/pubmed/32399548
http://dx.doi.org/10.1084/jem.20190742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336314/
https://www.ncbi.nlm.nih.gov/pubmed/32399548
http://dx.doi.org/10.1084/jem.20190742

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