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Blimp-1 is essential for allergen-induced asthma and Th2 cell development in the lung
A Th2 immune response is central to allergic airway inflammation, which afflicts millions worldwide. However, the mechanisms that augment GATA3 expression in an antigen-primed developing Th2 cell are not well understood. Here, we describe an unexpected role for Blimp-1, a transcriptional repressor t...
Autores principales: | He, Kun, Hettinga, Angela, Kale, Sagar Laxman, Hu, Sanmei, Xie, Markus M., Dent, Alexander L., Ray, Anuradha, Poholek, Amanda C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336314/ https://www.ncbi.nlm.nih.gov/pubmed/32399548 http://dx.doi.org/10.1084/jem.20190742 |
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