iPNHOT: a knowledge-based approach for identifying protein-nucleic acid interaction hot spots

BACKGROUND: The interaction between proteins and nucleic acids plays pivotal roles in various biological processes such as transcription, translation, and gene regulation. Hot spots are a small set of residues that contribute most to the binding affinity of a protein-nucleic acid interaction. Compar...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaolei, Liu, Ling, He, Jingjing, Fang, Ting, Xiong, Yi, Mitchell, Julie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336410/
https://www.ncbi.nlm.nih.gov/pubmed/32631222
http://dx.doi.org/10.1186/s12859-020-03636-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336410/
https://www.ncbi.nlm.nih.gov/pubmed/32631222
http://dx.doi.org/10.1186/s12859-020-03636-w

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