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iPNHOT: a knowledge-based approach for identifying protein-nucleic acid interaction hot spots
BACKGROUND: The interaction between proteins and nucleic acids plays pivotal roles in various biological processes such as transcription, translation, and gene regulation. Hot spots are a small set of residues that contribute most to the binding affinity of a protein-nucleic acid interaction. Compar...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336410/ https://www.ncbi.nlm.nih.gov/pubmed/32631222 http://dx.doi.org/10.1186/s12859-020-03636-w |