Mitochondrial APE1 promotes cisplatin resistance by downregulating ROS in osteosarcoma

Apurinic/apyrimidinic endonuclease 1 (APE1) is a primary nuclear-localized multifunctional protein in osteosarcoma. However, the cytoplasmic localization of APE1 was found to be functional and to increase with cisplatin resistance, yet the molecular mechanism is unknown. In the present study, we exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yufeng, Zhang, Zhimin, Li, Qing, Zhang, Liang, Cheng, Yi, Zhong, Zhaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336412/
https://www.ncbi.nlm.nih.gov/pubmed/32627008
http://dx.doi.org/10.3892/or.2020.7633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336412/
https://www.ncbi.nlm.nih.gov/pubmed/32627008
http://dx.doi.org/10.3892/or.2020.7633

Ejemplares similares