Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis

BACKGROUND: Animal models of non-alcoholic steatohepatitis (NASH) are important tools in preclinical research and drug discovery. Gubra-Amylin NASH (GAN) diet-induced obese (DIO) mice represent a model of fibrosing NASH. The present study directly assessed the clinical translatability of the model b...

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Detalles Bibliográficos
Autores principales: Hansen, Henrik H., Ægidius, Helene M., Oró, Denise, Evers, Simon S., Heebøll, Sara, Eriksen, Peter Lykke, Thomsen, Karen Louise, Bengtsson, Anja, Veidal, Sanne S., Feigh, Michel, Suppli, Malte P., Knop, Filip K., Grønbæk, Henning, Miranda, Diego, Trevaskis, James L., Vrang, Niels, Jelsing, Jacob, Rigbolt, Kristoffer T. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336447/
https://www.ncbi.nlm.nih.gov/pubmed/32631250
http://dx.doi.org/10.1186/s12876-020-01356-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336447/
https://www.ncbi.nlm.nih.gov/pubmed/32631250
http://dx.doi.org/10.1186/s12876-020-01356-2

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