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Cellular senescence mediates the detrimental effect of prenatal dexamethasone exposure on postnatal long bone growth in mouse offspring

BACKGROUND: Prenatal dexamethasone exposure (PDE) induces low birth weight and retardation of fetal bone development which are associated with lower peak bone mass in adult offspring. Here we evaluated whether and how PDE affects postnatal long bone growth in mouse offspring. METHODS: Pregnant mice...

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Detalles Bibliográficos
Autores principales: Su, Jianwen, Chai, Yu, Ji, Zhiguo, Xie, Yongheng, Yu, Bin, Zhang, Xianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336470/
https://www.ncbi.nlm.nih.gov/pubmed/32631432
http://dx.doi.org/10.1186/s13287-020-01790-9