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Cellular senescence mediates the detrimental effect of prenatal dexamethasone exposure on postnatal long bone growth in mouse offspring
BACKGROUND: Prenatal dexamethasone exposure (PDE) induces low birth weight and retardation of fetal bone development which are associated with lower peak bone mass in adult offspring. Here we evaluated whether and how PDE affects postnatal long bone growth in mouse offspring. METHODS: Pregnant mice...
Autores principales: | Su, Jianwen, Chai, Yu, Ji, Zhiguo, Xie, Yongheng, Yu, Bin, Zhang, Xianrong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336470/ https://www.ncbi.nlm.nih.gov/pubmed/32631432 http://dx.doi.org/10.1186/s13287-020-01790-9 |
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