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Mechanistic insight of predictive biomarkers for antitumor PD-1/PD-L1 blockade: A paradigm shift towards immunome evaluation

Checkpoint inhibitor-based immunotherapy has exhibited unprecedented success in the treatment of advanced-stage cancer in recent years. Several therapeutic antibodies targeting programmed death-1 (PD-1) or its ligand (PD-L1) have received regulatory approvals for the treatment of multiple malignanci...

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Detalles Bibliográficos
Autores principales: You, Wenjie, Shang, Bin, Sun, Jian, Liu, Xueqing, Su, Lili, Jiang, Shujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336519/
https://www.ncbi.nlm.nih.gov/pubmed/32627031
http://dx.doi.org/10.3892/or.2020.7643