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YC-1 sensitizes the antitumor effects of boron neutron capture therapy in hypoxic tumor cells

The uptake of boron into tumor cells is a key factor in the biological effects of boron neutron capture therapy (BNCT). The uptake of boron agents is suppressed in hypoxic conditions, but the mechanism of hypoxia-induced modulation of suppression of boron uptake is not clear. Therefore, we evaluated...

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Detalles Bibliográficos
Autores principales: Harada, Takaomi, Hirose, Katsumi, Wada, Yuki, Sato, Mariko, Ichise, Koji, Aoki, Masahiko, Kato, Takahiro, Takeda, Ken, Takai, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336550/
https://www.ncbi.nlm.nih.gov/pubmed/32367141
http://dx.doi.org/10.1093/jrr/rraa024