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YC-1 sensitizes the antitumor effects of boron neutron capture therapy in hypoxic tumor cells
The uptake of boron into tumor cells is a key factor in the biological effects of boron neutron capture therapy (BNCT). The uptake of boron agents is suppressed in hypoxic conditions, but the mechanism of hypoxia-induced modulation of suppression of boron uptake is not clear. Therefore, we evaluated...
Autores principales: | Harada, Takaomi, Hirose, Katsumi, Wada, Yuki, Sato, Mariko, Ichise, Koji, Aoki, Masahiko, Kato, Takahiro, Takeda, Ken, Takai, Yoshihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336550/ https://www.ncbi.nlm.nih.gov/pubmed/32367141 http://dx.doi.org/10.1093/jrr/rraa024 |
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