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Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway

BACKGROUND: Dormant chemotherapy-resistant leukemia cells can survive for an extended period before relapse. Nevertheless, the mechanisms underlying the development of chemoresistance in vivo remain unclear. METHODS: Using intravital bone imaging, we characterized the behavior of murine acute myeloi...

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Detalles Bibliográficos
Autores principales: Morimatsu, Maho, Yamashita, Erika, Seno, Shigeto, Sudo, Takao, Kikuta, Junichi, Mizuno, Hiroki, Okuzaki, Daisuke, Motooka, Daisuke, Ishii, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336645/
https://www.ncbi.nlm.nih.gov/pubmed/32665796
http://dx.doi.org/10.1186/s41232-020-00127-6