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Pulmonary endothelium-derived PD-L1 induced by the H9N2 avian influenza virus inhibits the immune response of T cells

BACKGROUND: The PD-1/PD-L1 pathway is an inhibitory signaling pathway that maintains the balance between the immune response and immunotolerance, and its overactivation in cancer and viral infections inhibits T cell function. The target cells of various viruses, microvascular endothelial cells (MECs...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Mu, Xiang, Dong, Hong, Hu, Ge, Zhang, Tao, He, Cheng, Siddique, Naila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336647/
https://www.ncbi.nlm.nih.gov/pubmed/32631356
http://dx.doi.org/10.1186/s12985-020-01341-x