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Pulmonary endothelium-derived PD-L1 induced by the H9N2 avian influenza virus inhibits the immune response of T cells
BACKGROUND: The PD-1/PD-L1 pathway is an inhibitory signaling pathway that maintains the balance between the immune response and immunotolerance, and its overactivation in cancer and viral infections inhibits T cell function. The target cells of various viruses, microvascular endothelial cells (MECs...
Autores principales: | Zhang, Qian, Mu, Xiang, Dong, Hong, Hu, Ge, Zhang, Tao, He, Cheng, Siddique, Naila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336647/ https://www.ncbi.nlm.nih.gov/pubmed/32631356 http://dx.doi.org/10.1186/s12985-020-01341-x |
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