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Exploring neighborhoods in large metagenome assembly graphs using spacegraphcats reveals hidden sequence diversity

Genomes computationally inferred from large metagenomic data sets are often incomplete and may be missing functionally important content and strain variation. We introduce an information retrieval system for large metagenomic data sets that exploits the sparsity of DNA assembly graphs to efficiently...

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Detalles Bibliográficos
Autores principales: Brown, C. Titus, Moritz, Dominik, O’Brien, Michael P., Reidl, Felix, Reiter, Taylor, Sullivan, Blair D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336657/
https://www.ncbi.nlm.nih.gov/pubmed/32631445
http://dx.doi.org/10.1186/s13059-020-02066-4