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Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathways in human lung tissue of smokers, COPD and IPF: Associations with SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 axis

Aging is one of the key contributing factors for chronic obstructive pulmonary diseases (COPD) and other chronic inflammatory lung diseases. Cigarette smoke is a major etiological risk factor that has been shown to alter cellular processes involving mitochondrial function, cellular senescence and te...

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Detalles Bibliográficos
Autores principales: Maremanda, Krishna P., Sundar, Isaac K., Li, Dongmei, Rahman, Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336702/
https://www.ncbi.nlm.nih.gov/pubmed/32702724
http://dx.doi.org/10.21203/rs.3.rs-35347/v1