Mutant COMP shapes growth and development of skull and facial structures in mice and humans

BACKGROUND: Cartilage oligomeric matrix protein (COMP) is an important extracellular matrix protein primarily functioning in the musculoskeletal tissues and especially endochondral bone growth. Mutations in COMP cause the skeletal dysplasia pseudoachondroplasia (PSACH) that is characterized by short...

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Detalles Bibliográficos
Autores principales: Burger, Alexander, Roosenboom, Jasmien, Hossain, Mohammad, Weinberg, Seth M., Hecht, Jacqueline T., Posey, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336729/
https://www.ncbi.nlm.nih.gov/pubmed/32347019
http://dx.doi.org/10.1002/mgg3.1251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336729/
https://www.ncbi.nlm.nih.gov/pubmed/32347019
http://dx.doi.org/10.1002/mgg3.1251

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