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Synthesis and crystal structures of 3-hy­droxy-2,4-dimethyl-2H-thio­phen-5-one and 3-hy­droxy-4-methyl-2H-thio­phen-5-one

The structures of two hy­droxy-thio­phenone derivatives related to the anti­biotic thiol­actomycin are presented. These are the racemic 3-hy­droxy-2,4-dimethyl-2H-thio­phen-5-one, C(6)H(8)O(2)S, and 3-hy­droxy-4-methyl-2H-thio­phen-5-one, C(5)H(6)O(2)S. The main structural feature of both compounds...

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Detalles Bibliográficos
Autores principales: Nashawi, Asma, Lawson, Christopher P., Abdel-Sattar, M. Omar, ter Horst, Joop H., Coxon, Geoffrey D., Kennedy, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336781/
https://www.ncbi.nlm.nih.gov/pubmed/32695472
http://dx.doi.org/10.1107/S2056989020008269