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15-Deoxy-Δ(12,14)-prostaglandin J(2) Induces Apoptosis in Ha-ras-transformed Human Breast Epithelial Cells by Targeting IκB kinase–NF-κB Signaling

15-Deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)), an endogenous ligand for PPARγ, has differential effects on cancer cell proliferation and survival depending on the dose and the type of cells. In the present study, we have investigated the effects of 15d-PGJ(2) on apoptosis of the Ha-ras transform...

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Detalles Bibliográficos
Autores principales: Na, Hye-Kyung, Yang, Hongkyung, Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337001/
https://www.ncbi.nlm.nih.gov/pubmed/32647651
http://dx.doi.org/10.15430/JCP.2020.25.2.100