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Gene expression profiling of epithelium-associated FcRL4(+) B cells in primary Sjögren’s syndrome reveals a pathogenic signature

In primary Sjögren’s syndrome (pSS), FcRL4(+) B cells are present in inflamed salivary gland tissue, within or in close proximity to ductal epithelium. FcRL4 is also expressed by nearly all pSS-related mucosa-associated lymphoid tissue (MALT) B cell lymphomas, linking FcRL4 expression to lymphomagen...

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Detalles Bibliográficos
Autores principales: Verstappen, Gwenny M., Ice, John A., Bootsma, Hendrika, Pringle, Sarah, Haacke, Erlin A., de Lange, Kim, van der Vries, Gerben B., Hickey, Peter, Vissink, Arjan, Spijkervet, Frederik K.L., Lessard, Christopher J., Kroese, Frans G.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337041/
https://www.ncbi.nlm.nih.gov/pubmed/32201227
http://dx.doi.org/10.1016/j.jaut.2020.102439