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A complex between the Zika virion and the Fab of a broadly cross-reactive neutralizing monoclonal antibody revealed by cryo-EM and single particle analysis at 4.1 Å resolution

Zika virus (ZIKV) recently emerged as a major public health concern because it can cause fetal microcephaly and neurological disease such as the Guillain-Barré syndrome. A particularly potent class of broadly neutralizing antibodies (nAbs) targets a quaternary epitope located at the interface of two...

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Detalles Bibliográficos
Autores principales: Tyagi, Anu, Ahmed, Tofayel, Shi, Jian, Bhushan, Shashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337043/
https://www.ncbi.nlm.nih.gov/pubmed/32647830
http://dx.doi.org/10.1016/j.yjsbx.2020.100028