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Specificity and regulation of phosphotyrosine signaling through SH2 domains

Phosphotyrosine (pY) signaling is instrumental to numerous cellular processes. pY recognition occurs through specialized protein modules, among which the Src-homology 2 (SH2) domain is the most common. SH2 domains are small protein modules with an invariant fold, and are present in more than a hundr...

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Detalles Bibliográficos
Autores principales: Marasco, Michelangelo, Carlomagno, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337045/
https://www.ncbi.nlm.nih.gov/pubmed/32647828
http://dx.doi.org/10.1016/j.yjsbx.2020.100026