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Structural insights into the activity and regulation of human Josephin-2

The MJD family of human deubiquitinating enzymes contains four members: Ataxin-3, the ataxin-3-like protein (AT3L), Josephin-1, and Josephin-2. All share a conserved catalytic unit known as the Josephin domain. Ataxin-3 and AT3L also contain extensive regulatory regions that modulate their functions...

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Detalles Bibliográficos
Autores principales: Grasty, Kimberly C., Weeks, Stephen D., Loll, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337049/
https://www.ncbi.nlm.nih.gov/pubmed/32647816
http://dx.doi.org/10.1016/j.yjsbx.2019.100011