Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand KITLG/SCF and Gene-By-Air-Pollution Interaction

Baseline lung function, quantified as forced expiratory volume in the first second of exhalation (FEV(1)), is a standard diagnostic criterion used by clinicians to identify and classify lung diseases. Using whole-genome sequencing data from the National Heart, Lung, and Blood Institute Trans-Omics f...

Descripción completa

Detalles Bibliográficos
Autores principales: Mak, Angel C. Y., Sajuthi, Satria, Joo, Jaehyun, Xiao, Shujie, Sleiman, Patrick M., White, Marquitta J., Lee, Eunice Y., Saef, Benjamin, Hu, Donglei, Gui, Hongsheng, Keys, Kevin L., Lurmann, Fred, Jain, Deepti, Abecasis, Gonçalo, Kang, Hyun Min, Nickerson, Deborah A., Germer, Soren, Zody, Michael C., Winterkorn, Lara, Reeves, Catherine, Huntsman, Scott, Eng, Celeste, Salazar, Sandra, Oh, Sam S., Gilliland, Frank D., Chen, Zhanghua, Kumar, Rajesh, Martínez, Fernando D., Wu, Ann Chen, Ziv, Elad, Hakonarson, Hakon, Himes, Blanca E., Williams, L. Keoki, Seibold, Max A., Burchard, Esteban G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337089/
https://www.ncbi.nlm.nih.gov/pubmed/32327564
http://dx.doi.org/10.1534/genetics.120.303231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337089/
https://www.ncbi.nlm.nih.gov/pubmed/32327564
http://dx.doi.org/10.1534/genetics.120.303231

Ejemplares similares