PD-L1 upregulation by IFN-α/γ-mediated Stat1 suppresses anti-HBV T cell response

Programmed death ligand 1 (PD-L1) has been recently shown to be a major obstacle to antiviral immunity by binding to its receptor programmed death 1 (PD-1) on specific IFN-γ producing T cells in chronic hepatitis B. Currently, IFN-α is widely used to treat hepatitis B virus (HBV) infection, but its...

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Detalles Bibliográficos
Autores principales: Liu, LanLan, Hou, Junwei, Xu, Yuxiu, Qin, Lijuan, Liu, Weiwei, Zhang, Han, Li, Yang, Chen, Mi, Deng, Mengmeng, Zhao, Bao, Hu, Jun, Zheng, Huaguo, Li, Changfei, Meng, Songdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337294/
https://www.ncbi.nlm.nih.gov/pubmed/32628668
http://dx.doi.org/10.1371/journal.pone.0228302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337294/
https://www.ncbi.nlm.nih.gov/pubmed/32628668
http://dx.doi.org/10.1371/journal.pone.0228302

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