Assessment of Proton-Coupled Conformational Dynamics of SARS and MERS Coronavirus Papain-like Proteases: Implication for Designing Broad-Spectrum Antiviral Inhibitors

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Broad-spectrum antiviral drugs are urgently needed to stop the COVID-19 pandemic and prevent future ones. The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is related to SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), which have caused the previous outbreak...

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Detalles Bibliográficos
Autores principales: Henderson, Jack A., Verma, Neha, Shen, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337382/
https://www.ncbi.nlm.nih.gov/pubmed/32637952
http://dx.doi.org/10.1101/2020.06.30.181305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337382/
https://www.ncbi.nlm.nih.gov/pubmed/32637952
http://dx.doi.org/10.1101/2020.06.30.181305

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