Glycans on the SARS-CoV-2 Spike Control the Receptor Binding Domain Conformation

The glycan shield of the beta-coronavirus (β-CoV) Spike (S) glycoprotein provides protection from host immune responses, acting as a steric block to potentially neutralizing antibody responses. The conformationally dynamic S-protein is the primary immunogenic target of vaccine design owing to its ro...

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Detalles Bibliográficos
Autores principales: Henderson, Rory, Edwards, Robert J, Mansouri, Katayoun, Janowska, Katarzyna, Stalls, Victoria, Kopp, Megan, Haynes, Barton F., Acharya, Priyamvada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337389/
https://www.ncbi.nlm.nih.gov/pubmed/32637959
http://dx.doi.org/10.1101/2020.06.26.173765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337389/
https://www.ncbi.nlm.nih.gov/pubmed/32637959
http://dx.doi.org/10.1101/2020.06.26.173765

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