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Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB
Efforts at host-directed therapy of tuberculosis have produced little control of the disease in experimental animals to date. This is not surprising, given that few specific host targets have been validated, and reciprocally, many of the compounds tested potentially impact multiple targets with both...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337396/ https://www.ncbi.nlm.nih.gov/pubmed/32574211 http://dx.doi.org/10.1371/journal.ppat.1008567 |