Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB

Efforts at host-directed therapy of tuberculosis have produced little control of the disease in experimental animals to date. This is not surprising, given that few specific host targets have been validated, and reciprocally, many of the compounds tested potentially impact multiple targets with both...

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Detalles Bibliográficos
Autores principales: Bryk, Ruslana, Mundhra, Shashirekha, Jiang, Xiuju, Wood, Madeleine, Pfau, Daniel, Weber, Elaina, Park, Suna, Zhang, Li, Wilson, Colin, Van der Westhuyzen, Renier, Street, Leslie, Chibale, Kelly, Zimmerman, Matthew, Dartois, Véronique, Pastore, Nunzia, Ballabio, Andrea, Hawryluk, Natalie, Canan, Stacie, Khetani, Vikram, Camardo, Joseph, Nathan, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337396/
https://www.ncbi.nlm.nih.gov/pubmed/32574211
http://dx.doi.org/10.1371/journal.ppat.1008567

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