Stress-induced phosphorylation of CLIP-170 by JNK promotes microtubule rescue

The stress-induced c-Jun N-terminal kinase (JNK) controls microtubule dynamics by enhancing both microtubule growth and rescues. Here, we show that upon cell stress, JNK directly phosphorylates the microtubule rescue factor CLIP-170 in its microtubule-binding domain to increase its rescue-promoting...

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Detalles Bibliográficos
Autores principales: Henrie, Hélène, Bakhos-Douaihy, Dalal, Cantaloube, Isabelle, Pilon, Antoine, Talantikite, Maya, Stoppin-Mellet, Virginie, Baillet, Anita, Poüs, Christian, Benoit, Béatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337496/
https://www.ncbi.nlm.nih.gov/pubmed/32491151
http://dx.doi.org/10.1083/jcb.201909093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337496/
https://www.ncbi.nlm.nih.gov/pubmed/32491151
http://dx.doi.org/10.1083/jcb.201909093

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