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LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation

Cilia and flagella are microtubule-based cellular projections with important sensory and motility functions. Their absence or malfunction is associated with a growing number of human diseases collectively referred to as ciliopathies. However, the fundamental mechanisms underpinning cilia biogenesis...

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Detalles Bibliográficos
Autores principales: Gonçalves, João, Sharma, Amit, Coyaud, Étienne, Laurent, Estelle M.N., Raught, Brian, Pelletier, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337498/
https://www.ncbi.nlm.nih.gov/pubmed/32496561
http://dx.doi.org/10.1083/jcb.201908132