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Dengue virus targets RBM10 deregulating host cell splicing and innate immune response

RNA-seq experiments previously performed by our laboratories showed enrichment in intronic sequences and alterations in alternative splicing in dengue-infected human cells. The transcript of the SAT1 gene, of well-known antiviral action, displayed higher inclusion of exon 4 in infected cells, leadin...

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Detalles Bibliográficos
Autores principales: Pozzi, Berta, Bragado, Laureano, Mammi, Pablo, Torti, María Florencia, Gaioli, Nicolás, Gebhard, Leopoldo G, García Solá, Martín E, Vaz-Drago, Rita, Iglesias, Néstor G, García, Cybele C, Gamarnik, Andrea V, Srebrow, Anabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337517/
https://www.ncbi.nlm.nih.gov/pubmed/32432721
http://dx.doi.org/10.1093/nar/gkaa340