Sequence-dependent dynamics of synthetic and endogenous RSSs in V(D)J recombination

Developing lymphocytes of jawed vertebrates cleave and combine distinct gene segments to assemble antigen–receptor genes. This process called V(D)J recombination that involves the RAG recombinase binding and cutting recombination signal sequences (RSSs) composed of conserved heptamer and nonamer seq...

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Detalles Bibliográficos
Autores principales: Hirokawa, Soichi, Chure, Griffin, Belliveau, Nathan M, Lovely, Geoffrey A, Anaya, Michael, Schatz, David G, Baltimore, David, Phillips, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337519/
https://www.ncbi.nlm.nih.gov/pubmed/32449932
http://dx.doi.org/10.1093/nar/gkaa418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337519/
https://www.ncbi.nlm.nih.gov/pubmed/32449932
http://dx.doi.org/10.1093/nar/gkaa418

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