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Synthetic promoter design in Escherichia coli based on a deep generative network
Promoter design remains one of the most important considerations in metabolic engineering and synthetic biology applications. Theoretically, there are 4(50) possible sequences for a 50-nt promoter, of which naturally occurring promoters make up only a small subset. To explore the vast number of pote...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337522/ https://www.ncbi.nlm.nih.gov/pubmed/32424410 http://dx.doi.org/10.1093/nar/gkaa325 |