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Synthetic promoter design in Escherichia coli based on a deep generative network

Promoter design remains one of the most important considerations in metabolic engineering and synthetic biology applications. Theoretically, there are 4(50) possible sequences for a 50-nt promoter, of which naturally occurring promoters make up only a small subset. To explore the vast number of pote...

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Detalles Bibliográficos
Autores principales: Wang, Ye, Wang, Haochen, Wei, Lei, Li, Shuailin, Liu, Liyang, Wang, Xiaowo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337522/
https://www.ncbi.nlm.nih.gov/pubmed/32424410
http://dx.doi.org/10.1093/nar/gkaa325