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Deep sequencing of non-enzymatic RNA primer extension

Life emerging in an RNA world is expected to propagate RNA as hereditary information, requiring some form of primitive replication without enzymes. Non-enzymatic template-directed RNA primer extension is a model of the copying step in this posited form of replication. The sequence space accessed by...

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Detalles Bibliográficos
Autores principales: Duzdevich, Daniel, Carr, Christopher E, Szostak, Jack W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337528/
https://www.ncbi.nlm.nih.gov/pubmed/32427335
http://dx.doi.org/10.1093/nar/gkaa400