MDM2’s dual mRNA binding domains co-ordinate its oncogenic and tumour suppressor activities

Cell growth requires a high level of protein synthesis and oncogenic pathways stimulate cell proliferation and ribosome biogenesis. Less is known about how cells respond to dysfunctional mRNA translation and how this feeds back into growth regulatory pathways. The Epstein-Barr virus (EBV)-encoded EB...

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Detalles Bibliográficos
Autores principales: Gnanasundram, Sivakumar Vadivel, Malbert-Colas, Laurence, Chen, Sa, Fusée, Leila, Daskalogianni, Chrysoula, Muller, Petr, Salomao, Norman, Fåhraeus, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337897/
https://www.ncbi.nlm.nih.gov/pubmed/32453417
http://dx.doi.org/10.1093/nar/gkaa431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337897/
https://www.ncbi.nlm.nih.gov/pubmed/32453417
http://dx.doi.org/10.1093/nar/gkaa431

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