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Nick-seq for single-nucleotide resolution genomic maps of DNA modifications and damage

DNA damage and epigenetic marks are well established to have profound influences on genome stability and cell phenotype, yet there are few technologies to obtain high-resolution genomic maps of the many types of chemical modifications of DNA. Here we present Nick-seq for quantitative, sensitive, and...

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Detalles Bibliográficos
Autores principales: Cao, Bo, Wu, Xiaolin, Zhou, Jieliang, Wu, Hang, Liu, Lili, Zhang, Qinghua, DeMott, Michael S, Gu, Chen, Wang, Lianrong, You, Delin, Dedon, Peter C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337925/
https://www.ncbi.nlm.nih.gov/pubmed/32484547
http://dx.doi.org/10.1093/nar/gkaa473