Lead-seq: transcriptome-wide structure probing in vivo using lead(II) ions

The dynamic conformation of RNA molecules within living cells is key to their function. Recent advances in probing the RNA structurome in vivo, including the use of SHAPE (Selective 2′-Hydroxyl Acylation analyzed by Primer Extension) or kethoxal reagents or DMS (dimethyl sulfate), provided unprecede...

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Detalles Bibliográficos
Autores principales: Twittenhoff, Christian, Brandenburg, Vivian B, Righetti, Francesco, Nuss, Aaron M, Mosig, Axel, Dersch, Petra, Narberhaus, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337928/
https://www.ncbi.nlm.nih.gov/pubmed/32463449
http://dx.doi.org/10.1093/nar/gkaa404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337928/
https://www.ncbi.nlm.nih.gov/pubmed/32463449
http://dx.doi.org/10.1093/nar/gkaa404

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