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Lead-seq: transcriptome-wide structure probing in vivo using lead(II) ions
The dynamic conformation of RNA molecules within living cells is key to their function. Recent advances in probing the RNA structurome in vivo, including the use of SHAPE (Selective 2′-Hydroxyl Acylation analyzed by Primer Extension) or kethoxal reagents or DMS (dimethyl sulfate), provided unprecede...
Autores principales: | Twittenhoff, Christian, Brandenburg, Vivian B, Righetti, Francesco, Nuss, Aaron M, Mosig, Axel, Dersch, Petra, Narberhaus, Franz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337928/ https://www.ncbi.nlm.nih.gov/pubmed/32463449 http://dx.doi.org/10.1093/nar/gkaa404 |
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