A bipartite thermodynamic-kinetic contribution by an activating mutation to RDF-independent excision by a phage serine integrase

Streptomyces phage ϕC31 integrase (Int)—a large serine site-specific recombinase—is autonomous for phage integration (attP x attB recombination) but is dependent on the phage coded gp3, a recombination directionality factor (RDF), for prophage excision (attL x attR recombination). A previously descr...

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Detalles Bibliográficos
Autores principales: Fan, Hsiu-Fang, Su, Bo-Yu, Ma, Chien-Hui, Rowley, Paul A, Jayaram, Makkuni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337939/
https://www.ncbi.nlm.nih.gov/pubmed/32479633
http://dx.doi.org/10.1093/nar/gkaa401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337939/
https://www.ncbi.nlm.nih.gov/pubmed/32479633
http://dx.doi.org/10.1093/nar/gkaa401

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