Cargando…
A bipartite thermodynamic-kinetic contribution by an activating mutation to RDF-independent excision by a phage serine integrase
Streptomyces phage ϕC31 integrase (Int)—a large serine site-specific recombinase—is autonomous for phage integration (attP x attB recombination) but is dependent on the phage coded gp3, a recombination directionality factor (RDF), for prophage excision (attL x attR recombination). A previously descr...
Autores principales: | Fan, Hsiu-Fang, Su, Bo-Yu, Ma, Chien-Hui, Rowley, Paul A, Jayaram, Makkuni |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337939/ https://www.ncbi.nlm.nih.gov/pubmed/32479633 http://dx.doi.org/10.1093/nar/gkaa401 |
Ejemplares similares
-
Single-molecule analysis of ϕC31 integrase-mediated site-specific recombination by tethered particle motion
por: Fan, Hsiu-Fang, et al.
Publicado: (2016) -
Real-time single-molecule tethered particle motion analysis reveals mechanistic similarities and contrasts of Flp site-specific recombinase with Cre and λ Int
por: Fan, Hsiu-Fang, et al.
Publicado: (2013) -
Coiled-coil interactions mediate serine integrase directionality
por: Gupta, Kushol, et al.
Publicado: (2017) -
Single molecule TPM analysis of the catalytic pentad mutants of Cre and Flp site-specific recombinases: contributions of the pentad residues to the pre-chemical steps of recombination
por: Fan, Hsiu-Fang, et al.
Publicado: (2015) -
Spermidine biases the resolution of Holliday junctions by phage λ integrase
por: Boldt, Jeffrey L., et al.
Publicado: (2007)