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Potential pharmacogenomic targets in bipolar disorder: considerations for current testing and the development of decision support tools to individualize treatment selection

BACKGROUND: Treatment in bipolar disorder (BD) is commonly applied as a multimodal therapy based on decision algorithms that lack an integrative understanding of molecular mechanisms or a biomarker associated clinical outcome measure. Pharmacogenetics/genomics study the individual genetic variation...

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Detalles Bibliográficos
Autores principales: Cuéllar-Barboza, Alfredo B., McElroy, Susan L., Veldic, Marin, Singh, Balwinder, Kung, Simon, Romo-Nava, Francisco, Nunez, Nicolas A., Cabello-Arreola, Alejandra, Coombes, Brandon J., Prieto, Miguel, Betcher, Hannah K., Moore, Katherine M., Winham, Stacey J., Biernacka, Joanna M., Frye, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338319/
https://www.ncbi.nlm.nih.gov/pubmed/32632502
http://dx.doi.org/10.1186/s40345-020-00184-3