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Potential pharmacogenomic targets in bipolar disorder: considerations for current testing and the development of decision support tools to individualize treatment selection
BACKGROUND: Treatment in bipolar disorder (BD) is commonly applied as a multimodal therapy based on decision algorithms that lack an integrative understanding of molecular mechanisms or a biomarker associated clinical outcome measure. Pharmacogenetics/genomics study the individual genetic variation...
Autores principales: | Cuéllar-Barboza, Alfredo B., McElroy, Susan L., Veldic, Marin, Singh, Balwinder, Kung, Simon, Romo-Nava, Francisco, Nunez, Nicolas A., Cabello-Arreola, Alejandra, Coombes, Brandon J., Prieto, Miguel, Betcher, Hannah K., Moore, Katherine M., Winham, Stacey J., Biernacka, Joanna M., Frye, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338319/ https://www.ncbi.nlm.nih.gov/pubmed/32632502 http://dx.doi.org/10.1186/s40345-020-00184-3 |
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