Peptide Bond Formation Between the Hetrosubunits of ω-Transaminase, Alanine Dehydrogenase, and Formate Dehydrogenase Through Subunit Splicing Promoted by Heterodimerization of Leucine Zipper Motifs

For the multimeric enzymes R-ω-transaminase (RTA), alanine dehydrogenase (AlaDH), and formate dehydrogenase (FDH), peptide bond formation between the hetrosubunits has been achieved by the intein-mediated in vivo subunit splicing. The subunit ligation is triggered by the heterodimerization of an arg...

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Detalles Bibliográficos
Autores principales: Li, Rong, Chen, Yao, Du, Kun, Feng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338344/
https://www.ncbi.nlm.nih.gov/pubmed/32695764
http://dx.doi.org/10.3389/fbioe.2020.00686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338344/
https://www.ncbi.nlm.nih.gov/pubmed/32695764
http://dx.doi.org/10.3389/fbioe.2020.00686

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