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The cellular heat shock response monitored by chemical exchange saturation transfer MRI
CEST-MRI of the rNOE signal has been demonstrated in vitro to be closely linked to the protein conformational state. As the detectability of denaturation and aggregation processes on a physiologically relevant scale in living organisms has yet to be verified, the aim of this study was to perform hea...
Autores principales: | Kleimaier, Dennis, Goerke, Steffen, Nies, Cordula, Zaiss, Moritz, Kunz, Patrick, Bachert, Peter, Ladd, Mark E., Gottwald, Eric, Schad, Lothar R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338423/ https://www.ncbi.nlm.nih.gov/pubmed/32632120 http://dx.doi.org/10.1038/s41598-020-68022-1 |
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